avidin d solution Search Results


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Vector Laboratories pabpc1
a–d, Immunostaining for <t>PABPC1</t> in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.
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Vector Laboratories abc kit
a–d, Immunostaining for <t>PABPC1</t> in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.
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Vector Laboratories normal horse serum nhs
a–d, Immunostaining for <t>PABPC1</t> in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.
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Vector Laboratories rabbit normal serum
a–d, Immunostaining for <t>PABPC1</t> in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.
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Vector Laboratories avidin biotin blocking solution
a–d, Immunostaining for <t>PABPC1</t> in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.
Avidin Biotin Blocking Solution, supplied by Vector Laboratories, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


a–d, Immunostaining for PABPC1 in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.

Journal: Nature genetics

Article Title: Therapeutic modulation of eIF2α-phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

doi: 10.1038/ng.2853

Figure Lengend Snippet: a–d, Immunostaining for PABPC1 in the cervical spinal cord of control and ALS patients. a) PABPC1 is expressed in spinal cord motor neurons, and is localized throughout the cytoplasm in a diffuse pattern. b ) Occasionally PABPC1 cytoplasmic accumulations were observed in normal motorneurons (arrow). c) In ALS patient motor neurons, PABPC1 is present in distinct cytoplasmic and dense accumulations (arrow). d ) PABPC1 cytoplasmic accumulations were also observed in the ALS motorneurons where there was a clearing in the middle. Scale bars, 30 μm. e ) The number of motor neurons containing cytoplasmic accumulation of PABPC1 in ALS patients was significantly greater ( p =0.01, one-tailed Mann-Whitney test) than in motor neurons from controls. For quantification of accumulations of PABPC1 in individual normal versus ALS cases, see . n=5 controls, 4 ALS patients, mean ± s.e.m.

Article Snippet: The tissue was cut into 7 μm sections and PABPC1 was immunolocalized with antigen retrieval (Antigen unmasking solution, citric acid based, Vector Laboratories, catalog # H-3300) and the avidin-biotin complex detection method with 3,3-diaminobenzidine as the chromagen (Vectastain ABC detection kit, Vector Labs, catalog # PK-6100).

Techniques: Immunostaining, One-tailed Test, MANN-WHITNEY